Removing the radio itself is actually pretty easy. But to get to that point, you'll first have to remove some dash trim pieces. And there's usually a trick or two to getting those off without wrecking anything.
I recommend investing in two things: a set of special tools for trim removal and an online set of instructions geared specifically to your car. A set of the four most commonly used trim removal tools costs less than $16 online. It's worth every penny.
For help with the radio removal procedure for your vehicle, go to www.carstereohelp.com. This site sells complete radio and trim removal instructions (with photos) for over 4,000 different make/ model combinations. The removal instructions cost less than $10