First question, how many are miles on the truck? How many miles since the last cooling system service? How many miles or time since the radiator hoses and clamps were replaced?
Be sure the cooling system has been properly bled of any residual air. Other possible spots that can cause the system to lose pressure due to leaks are: the bypass tube located behind the t-stat housing where the housing connects to the block. The hoses that connect to the throttle body under the upper intake manifold. As well as Check the hoses in between the firewall and the upper intake manifold. Check the coolant overflow tank for cracks.
Leaks that occur in those areas can many times be extremely difficult to notice since the majority of the coolant that leaks out quickly evaporates in contact with the hot engine.
Evaporated coolant, as you are probably already aware of, leaves white spots where the coolant has evaporated.
Make a careful visual inspection of the entire cooling system, and then PRESSURE TEST the cooling system and radiator cap. A pressure test will reveal internal leaks such as seepage past the head gasket as well as cracks in the head or block. A good system should hold 12 to 15 psi for 15 minutes or more with no loss in pressure. If it leaks pressure, there is an internal coolant leak (most likely a bad head gasket but possibly also a cracked cylinder or engine block).
It is important to pressure test the radiator cap, too, because a weak cap (or one with too low a pressure rating.
1. Perform a cooling system / radiator pressure test when the engine is cold - as a first step to locate the leak.
Obtain a loaner tool / free radiator pressure tester from the local auto parts stores such as; Autozone, O'Reilly, NAPA, Advance Auto, or PepBoys. Follow their instructions and pump it to an adequate air pressure 12 -15 psi or the pressure rating listed on the radiator or reservoir cap. Observe the leaks and perform the repair.
Note: do not over pressurize beyond the pressure allowed by the radiator cap, then test the radiator cap as well.
2. Air pockets trapped in the cooling system can cause the engine to overheat. Some cooling systems have air bleed valves built into the system to aid in the removal of air pockets. Advice: For many cooling systems, the method of removing air pockets is to start the engine and allow it to run with the radiator cap off or loose until all the air escapes from the neck of the radiator. For some systems this method is not sufficient, and the manufacturer has installed air bleed valves usually near or on the thermostat housing.